Project Summary ? Administrative Core The Administrative Core will oversee the daily running of all resource core components and their staff, and administer the Core research grant. An Advisory Group, consisting of the PI and the Directors and technicians of each Resource Component, will meet on a 3-monthly basis to discuss any issues related to the Core instruments, technical support and overall usage. This advisory group will consult with an External Advisory Group, made up of highly-respected vision researchers who are directors of components of the NEI core grants held at their respective institutions, in California. Mechanisms to optimize usage and productivity by the core investigators will be addressed regularly. Information on the instruments and services available from the Resource Components are available on a newly-established web site. Investigators schedule their usage of Core facilities, through a secure link from the website. All usage is thus recorded in electronic log books. Administration of the Core grant, with respect to accounting and reporting will be performed by a Grant's Analyst, in coordination with the PI.